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Elsevier Spotlight
The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) trial was designed to prospectively study the relationship between change in natriuretic peptide concentration, cardiac remodeling, and clinical events in patients with heart failure with reduced ejection fraction (HFrEF). The trial was stopped early because biomarker-guided treatment was not more effective than usual care in improving outcomes. The GUIDE-IT Echo Substudy was a prespecified substudy designed to understand the influence of biomarker-guided therapy on cardiac structure and function.
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Advances in Family Practice Nursing is the newest addition to the Elsevier Advances family. It continues the tradition of publishing original articles on current advances and breakthroughs within a specialty.
Elsevier Spotlight
The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) trial was designed to prospectively study the relationship between change in natriuretic peptide concentration, cardiac remodeling, and clinical events in patients with heart failure with reduced ejection fraction (HFrEF). The trial was stopped early because biomarker-guided treatment was not more effective than usual care in improving outcomes. The GUIDE-IT Echo Substudy was a prespecified substudy designed to understand the influence of biomarker-guided therapy on cardiac structure and function.
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This is a welcome addition to the library of any practicing pulmonologist. Highly recommended. MORE

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