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Early identification of coronary artery disease (CAD) is difficult using traditional risk factors and risk scores. While it is well known that CAD has substantial heritability and a polygenic architecture, genomic risk scores to help predict early CAD have yet to be shown especially effective. In this study, Inouye et al constructed a genomic risk score based on 1.7 million single nucleotide polymorphisms (SNPs) to predict lifetime risk trajectories for CAD. The researchers developed built a new genomic risk score for CAD (called metaGRS) using a meta-analytic approach to combine large-scale, genome-wide, and targeted genetic association data. The score was based on 3 other genetic risk scores and included 1.7 million genetic variants. MORE

Esteemed Elsevier author, Meir Kryger, MD, FRCP, is a Professor of Pulmonary Medicine and Clinical Professor of Nursing at the Yale School of Medicine. Dr. Kryger is a trailblazer in the field of sleep medicine. MORE

Elsevier author and famed ophthalmologist, Jack J. Kanski, MD, MS, FRCS, FRCOphth, passed away January 5th, 2019 at the age of 79. Dr. Kanski was the author of more than 30 ophthalmology textbooks, including Kanski’s Clinical Ophthalmology, Synopsis Of Clinical Ophthalmology, Signs In Ophthalmology: Causes And Differential, and Test Yourself Atlas In Ophthalmology. He also authored several books on world history. Dr. Kanski was born in Warsaw, Poland. He obtained his Bachelor of Medicine and Bachelor of Science degrees from London Hospital Medical School in England in 1963. He held positions at multiple hospitals in London, most notably serving as Honorary Consultant and Ophthalmic Surgeon at King Edward VII Hospital in Windsor, England, where he spent over 25 years. He was awarded an honorary fellowship by the Royal College of Ophthalmologists in 2004. He will be forever remembered as one of the most respected authors in the field of ophthalmology. MORE

Surgical Clinics is proud to announce the December 2018 publication of a comprehensive volume on Enhanced Recovery After Surgery (ERAS). ERAS is a set of protocols used by the surgical team to help ensure a patient has the best possible outcome from their surgery, and ERAS programs have been shown to be more safe and effective relative to traditional care. MORE

Advances in Molecular Pathology provides readers with an in-depth review of the latest clinical advancements in seven subspecialty areas, which are Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid Tumors, and Identity/HLA. MORE