The bottom line is that soaking a Hamstring graft during surgery in a Vancomycin saline solution (500mg Vancomycin in 100cc NS) has been shown to completely eradicate HS ACLR infection.  There are 4 relevant recent papers on this point below. The abstracts are linked below.  

1. et al found that HS grafts had a 1.52% infection rate vs 1.03% for BTB grafts. This half percent difference is obviously quite small but has caused some to avoid HS grafts
2. et al in 2012 found that soaking the grafts in Vancomycin during surgery eliminated infections, whereas without Vancomycin the infection rate was 1.4%. et al from this same group in Australia published a larger follow-up study in 2017 with essentially identical results
3. et al found that 22% of grafts were culture positive.

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