Interview with José Jalife MD, PhD
Why did you feel that it was important to write the eighth edition of Cardiac Electrophysiology from Cell to Bedside? What does the publication add to the field?
Since 1985, this text has been and continues to be the “bible” of cardiac electrophysiology and arrhythmology. It covers a wide range of topics in such fields, from the most fundamental aspects of cardiac electrical function, including the biophysics of ion channels and their regulation through basic mechanisms of arrhythmias to everything the clinical electrophysiologist must know about atrial and ventricular arrhythmias.
What is the most exciting aspect of the new edition? What chapter or topic covered are you most excited about?
The 8th edition is fully updated, with 137 chapters describing the state-of-the-art in cardiac electrophysiology from the molecule to the bedside. Forty-seven chapters are completely new.
Who will find the greatest value from this book and why?
Basic electrophysiologists, biophysicists, pharmacologists, translational electrophysiologists, cardiologists, cardiac electrophysiologists, internists, anesthesiologists, clinical EP fellows, postdoctoral fellows and PhD students.
What new ideas, practices, or procedures do you hope your readers take away from your text?
The basic and translational electrophysiologist will find chapters describing theoretical and experimental results using the most advanced technologies, like near-atomic in-silico modeling of cardiac ion channels, genomics, proteomics, CRISPR-CAS9 gene editing, patch-clamping, confocal microscopy, immunofluorescence microscopy, molecular imaging optical mapping, iPSC-CM (induced pluripotent stem cell-derived cardiomyocyte) technology, embryonic stem cells, zebrafish, precision medicine.
The clinician will find the latest on atrial fibrillation and stroke prevention, new advances in understanding ventricular arrhythmias in inherited diseases, advances in personal cardiac monitoring and integrated devices, noninvasive ECG imaging, understanding and diagnosis of arrhythmia, genetic testing and channelopathies, recent advances in the management wearable devices, antiarrhythmic drugs, radiofrequency ablation, cryoablation and other radiofrequency alternatives, ethanol ablation, radioablation, epicardial approach in electrophysiology, surgery for atrial and ventricular arrhythmias, and neuromodulation for the treatment of arrhythmias.
About the Editor
José Jalife MD, PhD
Distinguished Senior Investigator, Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Emeritus Professor of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
I am a physician scientist interested in translational cardiac electrophysiology.
I have had the honor of knowing Dr. Jalife and his work for decades. Every ‘Cell to Bedside’ I have bought. Dr. Jalife with his colleagues has given to the clinician the strongest background and window into the future in basic electrophysiology. Perspective and depth, merged with the ability to clearly communicate original thought to all of us in cardiology (I am a veterinary cardiologist); this is the leadership in publication that Dr. Jalife produces and inspires. Hooray for Pepe!